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1

The discovery of α1-antitrypsin and its role in health and disease

Sabina M. Janciauskiene, Robert Bals, Rembert Koczulla, Claus Vogelmeier, Thomas Köhnlein, Tobias Welte

Journal:

Respiratory Medicine

Year:

2011

Language:

english

File:

PDF, 587 KB

english, 2011

2

Atorvastatin Reduces Plasma Levels of Chemokine (CXCL10) in Patients with Crohn's Disease

Grip, Olof, Janciauskiene, Sabina, Timmer, Antje

Journal:

Year:

2009

Language:

english

File:

PDF, 134 KB

english, 2009

3

Advances in Identifying Urine/Serum Biomarkers in Alpha-1 Antitrypsin Deficiency for More Personalized Future Treatment Strategies

Ferrarotti, Ilaria, Corsico, Angelo Guido, Stolk, Jan, Ottaviani, Stefania, Fumagalli, Marco, Janciauskiene, Sabina, Iadarola, Paolo

Journal:

COPD Journal of Chronic Obstructive Pulmonary Disease

Year:

2016

Language:

english

File:

PDF, 723 KB

english, 2016

4

Heme as a Target for Therapeutic Interventions

Immenschuh, Stephan, Vijayan, Vijith, Janciauskiene, Sabina, Gueler, Faikah

Journal:

Frontiers in Pharmacology

Year:

2017

Language:

english

File:

PDF, 1.18 MB

english, 2017

5

Inflammation, antichymotrypsin, and lipid metabolism: autogenic etiology of alzheimer's disease

S. Janciauskiene, H.T. Wright

Journal:

Year:

1998

Language:

english

File:

PDF, 209 KB

english, 1998

6

Sera from anti–Jo-1–positive patients with polymyositis and interstitial lung disease induce expression of intercellular adhesion molecule 1 in human lung endothelial cells

Sevim Barbasso Helmers, Pernilla Englund, Marianne Engström, Erik Åhlin, Maryam Fathi, Sabina Janciauskiene, Mikael Heimbürger, Johan Rönnelid, Ingrid E. Lundberg

Journal:

Arthritis & Rheumatism

Year:

2009

Language:

english

File:

PDF, 138 KB

english, 2009

7

N-glycosylation and biological activity of recombinant human alpha1-antitrypsin expressed in a novel human neuronal cell line

Véronique Blanchard, Xi Liu, Susann Eigel, Matthias Kaup, Silke Rieck, Sabina Janciauskiene, Volker Sandig, Uwe Marx, Peter Walden, Rudolf Tauber, Markus Berger

Journal:

Biotechnology and Bioengineering

Year:

2011

Language:

english

File:

PDF, 747 KB

english, 2011

8

Binding and uptake of Aβ1-42 by primary human astrocytes in vitro

Henrietta M. Nielsen, Robert Veerhuis, Bo Holmqvist, Sabina Janciauskiene

Journal:

Year:

2009

Language:

english

File:

PDF, 532 KB

english, 2009

9

Differential detection of PAS-positive inclusions formed by the Z, Siiyama, and Mmalton variants of α1-antitrypsin

Sabina Janciauskiene, Sten Eriksson, Francesco Callea, Meera Mallya, Aiwu Zhou, Kuniaki Seyama, Satoru Hata, David A. Lomas

Journal:

Year:

2004

Language:

english

File:

PDF, 591 KB

english, 2004

10

Effects of fibrillar C-terminal fragment of cleaved α1-antitrypsin on cholesterol homeostasis in HepG2 cells

Sabina Janciauskiene, Stefan Lindgren

Journal:

Year:

1999

Language:

english

File:

PDF, 251 KB

english, 1999

11

α1-Antichymotrypsin/Alzheimer's peptide Aβ1–42 complex perturbs lipid metabolism and activates transcription factors PPARγ and NFκB in human neuroblastoma (Kelly) cells

Yong-Xin Sun, H.T. Wright, S. Janciauskiene

Journal:

Journal of Neuroscience Research

Year:

2002

Language:

english

File:

PDF, 948 KB

english, 2002

12

α1-Antitrypsin inhibits Moraxella catarrhalis MID protein-induced tonsillar B cell proliferation and IL-6 release

Radinka Hadzic, Izabela Nita, Helena Tassidis, Kristian Riesbeck, Anette Gjörloff Wingren, Sabina Janciauskiene

Journal:

Immunology Letters

Year:

2006

Language:

english

File:

PDF, 230 KB

english, 2006

13

Alzheimer’s peptide: A possible link between glaucoma, exfoliation syndrome and Alzheimer’s disease

Sabina Janciauskiene, Torsten Krakau

Journal:

Acta Ophthalmologica (Blackwell)

Year:

2001

Language:

english

File:

PDF, 38 KB

english, 2001

14

Alpha-1-antitrypsin is present in the specific granules of human eosinophilic granulocytes

B. Johansson, J. Malm, T. Persson, S. Janciauskiene, P. Andersson, J. Carlson, A. Egesten

Journal:

Clinical & Experimental Allergy

Year:

2001

Language:

english

File:

PDF, 345 KB

english, 2001

15

Human monocyte activation by cleaved form of alpha-1-antitrypsin : Involvement of the phagocytic pathway

Sabina Janciauskiene, Stefan Lindgren

Journal:

Year:

1999

Language:

english

File:

PDF, 531 KB

english, 1999

16

Concentration-dependent effects of native and polymerised α1-antitrypsin on primary human monocytes,in vitro

Ruta Aldonyte, Lennart Jansson, Sabina Janciauskiene

Journal:

BMC Cell Biology

Year:

2004

Language:

english

File:

PDF, 448 KB

english, 2004

17

Antibodies against gonadotropin-releasing hormone (GnRH) and destruction of enteric neurons in 3 patients suffering from gastrointestinal dysfunction

Bodil Ohlsson, Eva Ekblad, Béla Veress, Agneta Montgomery, Sabina Janciauskiene

Journal:

BMC Gastroenterology

Year:

2010

Language:

english

File:

PDF, 718 KB

english, 2010

18

Lymphocyte and monocyte flow cytometry immunophenotyping as a diagnostic tool in uncharacteristic inflammatory disorders

Helena Janols, Anders Bredberg, Irene Thuvesson, Sabina Janciauskiene, Olof Grip, Marlene Wullt

Journal:

BMC Infectious Diseases

Year:

2010

Language:

english

File:

PDF, 595 KB

english, 2010

19

Plasma levels of alpha1-antichymotrypsin and secretory leukocyte proteinase inhibitor in healthy and chronic obstructive pulmonary disease (COPD) subjects with and without severe α1-antitrypsin deficiency

Camilla Hollander, Ulla Westin, Anders Wallmark, Eeva Piitulainen, Tomas Sveger, Sabina M Janciauskiene

Journal:

BMC Pulmonary Medicine

Year:

2007

Language:

english

File:

PDF, 498 KB

english, 2007

20

Human mast cells decrease SLPI levels in type II – like alveolar cell model,in vitro

Camilla Hollander, Max Nyström, Sabina Janciauskiene, Ulla Westin

Journal:

Cancer Cell International

Year:

2003

Language:

english

File:

PDF, 684 KB

english, 2003

21

α1-antitrypsin and its C-terminal fragment attenuate effects of degranulated neutrophil-conditioned medium on lung cancer HCC cells,in vitro

Inga Zelvyte, Tim Stevens, Ulla Westin, Sabina Janciauskiene

Journal:

Cancer Cell International

Year:

2004

Language:

english

File:

PDF, 1.63 MB

english, 2004

22

Atorvastatin activates PPAR-γ and attenuates the inflammatory response in human monocytes

O. Grip, S. Janciauskiene, S. Lindgren

Journal:

Inflammation Research

Year:

2002

Language:

english

File:

PDF, 667 KB

english, 2002

23

Glioma cell activation by Alzheimer's peptide Aβ1–42,α1-antichymotrypsin, and their mixture

Y. X. Sun, H. T. Wright, S. Janciauskiene

Journal:

Cellular and Molecular Life Sciences

Year:

2002

Language:

english

File:

PDF, 200 KB

english, 2002

24

Effects of alpha 1-antitrypsin on endotoxin-induced lung inflammation in

Devipriya Subramaniyam, Chad Steele, Thomas Köhnlein, Tobias Welte, Olof Grip, Sadis Matalon, Sabina Janciauskiene

Journal:

Inflammation Research

Year:

2010

Language:

english

File:

PDF, 247 KB

english, 2010

25

Fibrillogenic C-terminal fragment of alpha-1-antitrypsin activates human monocytes via oxidative mechanisms

D. Bironaite, S. Lindgren, S. Janciauskiene

Journal:

Cell and Tissue Research

Year:

2001

Language:

english

File:

PDF, 243 KB

english, 2001

26

Low plasma levels of monocyte chemoattractant protein-1 (MCP-1), tumor necrosis factor-alpha (TNFα), and vascular endothelial growth factor (VEGF) in patients with alpha1-antitrypsin deficiency-related fibromyalgia

Ignacio Blanco, Sabina Janciauskiene, Izabela Nita, Enrique Fernández-Bustillo, Victoriano Cárcaba, César Gallo, Marlene Álvarez-Rico, Frederick de Serres, Nana Béridze

Journal:

Clinical Rheumatology

Year:

2010

Language:

english

File:

PDF, 183 KB

english, 2010

27

Abnormal overexpression of mastocytes in skin biopsies of fibromyalgia patients

Ignacio Blanco, Nana Béritze, Mario Argüelles, Victoriano Cárcaba, Fernando Fernández, Sabina Janciauskiene, Katerina Oikonomopoulou, Frederick J. de Serres, Enrique Fernández-Bustillo, Morley D. Holl

Journal:

Clinical Rheumatology

Year:

2010

Language:

english

File:

PDF, 403 KB

english, 2010

28

Polymerized α1-antitrypsin is present on lung vascular endothelium. New insights into the biological significance of α1-antitrypsin polymerization

R Aldonyte, L Jansson, O Ljungberg, S Larsson, S Janciauskiene

Journal:

Year:

2004

Language:

english

File:

PDF, 567 KB

english, 2004

29

Secretory leukocyte protease inhibitor inhibits neutrophil apoptosis

Devipriya SUBRAMANIYAM, Camilla HOLLANDER, Ulla WESTIN, Jonas ERJEFÄLT, Tim STEVENS, Sabina JANCIAUSKIENE

Journal:

Year:

2011

Language:

english

File:

PDF, 393 KB

english, 2011

30

An association between Type 2 diabetes and α1-antitrypsin deficiency

C. S. Sandström, B. Ohlsson, O. Melander, U. Westin, R. Mahadeva, S. Janciauskiene

Journal:

Diabetic Medicine

Year:

2008

Language:

english

File:

PDF, 125 KB

english, 2008

31

Use of atorvastatin as an anti-inflammatory treatment in Crohn's disease

O Grip, S Janciauskiene, A Bredberg

Journal:

British Journal of Pharmacology

Year:

2008

Language:

english

File:

PDF, 243 KB

english, 2008

32

Clinical utility gene card for: α-1-antitrypsin deficiency

Janciauskiene, Sabina, Ferrarotti, Ilaria, Laenger, Florian, Jonigk, Danny, Luisetti, Maurizio

Journal:

European Journal of Human Genetics

Year:

2011

Language:

english

File:

PDF, 168 KB

english, 2011

33

A specific structural interaction of Alzheimer's peptide Aβ1–42 with α1-antichymotrypsin

Janciauskiene, Sabina, Eriksson, Sten, Wright, H. Tonie

Journal:

Natural Structural Biology

Year:

1996

File:

PDF, 545 KB

1996

34

Circulating monocytes and plasma inflammatory biomarkers in active Crohn's disease. Elevated oxidized low-density lipoprotein and the anti-inflammatory effect of atorvastatin

Olof Grip, Sabina Janciauskiene, Stefan Lindgren

Journal:

Inflammatory Bowel Diseases

Year:

2004

Language:

english

File:

PDF, 210 KB

english, 2004

35

Alzheimer's peptide and serine proteinase inhibitors in glaucoma and exfoliation syndrome

Sabina Janciauskiene, Torsten Krakau

Journal:

Documenta Ophthalmologica

Year:

2003

Language:

english

File:

PDF, 300 KB

english, 2003

36

239: Preeclampsia is a disease characterized by specific supramolecular aggregates of misfolded proteins and congophilia

Irina A. Buhimschi, Guomao Zhao, Margaret A. Baumbusch, Sabina Janciauskiene, Catalin S. Buhimschi

Journal:

American Journal of Obstetrics and Gynecology

Year:

2008

Language:

english

File:

PDF, 56 KB

english, 2008

37

Correlation between p53 protein expression and other molecular markers influencing the metastatic breast cancer outcomes

Sigita Liutkauskienė, Elona Juozaitytė, Darius Pranys, Lina Poškienė, Kristina Jurėnienė, Rasa Jančiauskienė

Journal:

Year:

2011

Language:

english

File:

PDF, 60 KB

english, 2011

38

Soluble adhesion molecules and angiotensin-converting enzyme in dementia

Henrietta M. Nielsen, Elisabet Londos, Lennart Minthon, Sabina M. Janciauskiene

Journal:

Neurobiology of Disease

Year:

2007

Language:

english

File:

PDF, 423 KB

english, 2007

39

rCBF pathology in Alzheimer's disease is associated with slow processing speed

S. Warkentin, C. Erikson, S. Janciauskiene

Journal:

Neuropsychologia

Year:

2008

Language:

english

File:

PDF, 306 KB

english, 2008

40

Augmentation therapy in emphysema patient with ZZ α-1-antitrypsin deficiency

Caroline S. Sandström, Eeva Piitulainen, Sabina Janciauskiene

Journal:

Respiratory Medicine CME

Year:

2008

Language:

english

File:

PDF, 539 KB

english, 2008

41

Pravastatin down-regulates inflammatory mediators in human monocytes in vitro

Olof Grip, Sabina Janciauskiene, Stefan Lindgren

Journal:

European Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 867 KB

english, 2000

42

Effects of native and cleaved forms of α1-antitrypsin on ME 1477 tumor cell functional activity

Inga Zelvyte, Hans-Olov Sjögren, Sabina Janciauskiene

Journal:

Cancer Detection and Prevention

Year:

2002

Language:

english

File:

PDF, 366 KB

english, 2002

43

The C-terminal peptide of α-1-antitrypsin increases low density lipoprotein binding in HepG2 cells

Sabina Janciauskiene, Stefan Lindgren, H. Tonie Wright

Journal:

Year:

1998

Language:

english

File:

PDF, 768 KB

english, 1998

44

Fibrillar Alzheimer’s amyloid peptide A β1–42stimulates low density lipoprotein binding and cell association, free radical production and cell cytotoxicity in PC12 cells

S. Janciauskiene, H.T. Wright, S. Lindgren

Journal:

Year:

1999

Language:

english

File:

PDF, 149 KB

english, 1999

45

An interaction between Gemfibrozil and alpha1-antitrypsin

S. JANCIAUSKIENE, S. ERIKSSON

Journal:

Journal of Internal Medicine

Year:

1994

Language:

english

File:

PDF, 528 KB

english, 1994

46

The putative role of alpha-1-antitrypsin in the disaggregation of amyloid lambda fibrils

S. ERIKSSON, S. JANCIAUSKIENE, G. MERLINI

Journal:

Journal of Internal Medicine

Year:

1995

Language:

english

File:

PDF, 1.10 MB

english, 1995

47

The impact of age on post-operative outcomes of colorectal cancer patients undergoing surgical treatment

Tadas Latkauskas, Giedrė Rudinskaitė, Juozas Kurtinaitis, Rasa Jančiauskienė, Algimantas Tamelis, Žilvinas Saladžinskas, Dainius Pavalkis

Journal:

Year:

2005

Language:

english

File:

PDF, 400 KB

english, 2005

48

Initial results of a randomized controlled trial comparing clinical and pathological downstaging of rectal cancer after preoperative short-course radiotherapy or long-term chemoradiotherapy, both with delayed surgery

T. Latkauskas, H. Pauzas, I. Gineikiene, R. Janciauskiene, E. Juozaityte, Z. Saladzinskas, A. Tamelis, D. Pavalkis

Journal:

Colorectal Disease

Year:

2012

Language:

english

File:

PDF, 57 KB

english, 2012

49

Thein VitroEffect of Lithocholic Acid on the Polymerization Properties of PiZ Alpha-1-Antitrypsin

Marie-Christine Gerbod, Sabina Janciauskiene, Jan-Olof Jeppsson, Sten Eriksson

Journal:

Archives of Biochemistry and Biophysics

Year:

1998

Language:

english

File:

PDF, 202 KB

english, 1998

50

Effects of Noninhibitory α-1-Antitrypsin on Primary Human Monocyte Activation in Vitro

Fabian Moraga, Stefan Lindgren, Sabina Janciauskiene

Journal:

Archives of Biochemistry and Biophysics

Year:

2001

Language:

english

File:

PDF, 74 KB

english, 2001

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